Are you a man suffering from Post-Finasteride Syndrome (PFS)? This severe, persistent, and potentially permanent disorder is characterized by hormonal changes that cause sexual and mental dysfunction. Many men who took finasteride in Propecia or Proscar now suffer from Post-Finasteride Syndrome. Merck & Co., the pharmaceutical company responsible for finasteride injuries, now faces an onslaught of Post Finasteride-Syndrome Lawsuits brought by men seeking justice and compensation for their injuries.
Do I Have a Post-Finasteride Syndrome Lawsuit? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one has been injured after taking finasteride, you should contact our lawyers immediately. You may be entitled to compensation by filing a Post-Finasteride Syndrome lawsuit.
April 11, 2012: Today, the U.S. Food and Drug Administration (FDA) announced that the agency will be updating Propecia labels to include more warnings about the risk of persistent, severe sexual side effects that do not resolve when Propecia is discontinued. After receiving hundreds of reports from men who were injured by Propecia, the new labels will warn about the possible risk of libido disorders, orgasm disorders, and ejaculation disorders. The FDA will also warn that while men are taking Propecia, they may have fertility problems and decreased quality of semen.
Finasteride is the active ingredient in two popular medications: Proscar and Propecia. It was originally used in 5-mg doses in Proscar, a drug used to shrink an enlarged male prostate gland. When physicians noted that men taking Proscar tended to stop losing their hair, finasteride was re-developed as a prescription medication for the treatment of male-pattern baldness. Around 50-60% of the male population suffers from male-pattern baldness. Propecia is the only prescription medication that is FDA-approved to treat this condition.
When finasteride was approved, the FDA and Merck & Co. already knew that it could have adverse effects on a man’s sexual well-being. Studies had estimated that the risk was relatively low (around 2% of men), and doctors assumed that once the men stopped taking finasteride, the side effects would disappear and men would return to their pre-finasteride sexual health.
Unfortunately, there is growing evidence linking finasteride to persistent sexual dysfunction. In 2008, Swedish researchers found a link between finasteride and persistent erectile dysfunction. Health authorities in Sweden, Italy, and the United Kingdom required Merck & Co. to update the safety labeling. However, Merck waited until April 2011 to make the same changes to the labels in the United States.
Many men are angry at Merck for waiting to update the labels in the United States. However, this is not their only concern. Many men are now suffering from far more severe problems that just persistent erectile dysfunction. They are now calling their disorder Post-Finasteride Syndrome.
Post-Finasteride Syndrome is a disorder characterized by persistent, potentially permanent changes to a man’s hormonal chemistry that results in dramatic changes to a man’s sexual and emotional well-being. Men with PFS typically have significantly lower levels of testosterone, a condition called “hypogonadism” (glands have reduced or eliminated production of male sex hormones), and their condition does not respond to traditional treatments that usually correct this condition.
Though these men were reassured that their sexual dysfunction would resolve after taking finasteride, many of these men have suffered side effects for months or years after stopping finasteride.
Many men believe that the reason they have continued to experience side effects is because finasteride makes dramatic changes to the brain’s chemistry. Finasteride inhibits an enzyme called 5-alpha reductase, which the body needs to convert testosterone into dihydrotestosterone (DHT). For men who are genetically predisposed to suffer from male pattern baldness, their hair follicles shut down when they come in contact with DHT. Because finasteride inhibits 5-alpha reductase, the body is unable to produce most DHT, and DHT levels drop by around 70%.
One physical side effect of this is an end to hair loss. Other physical side effects are related to the significant reduction of DHT in the body, which is involved in male sexual health.
Side Effects of Post-Finasteride Syndrome
Many men who have taken finasteride have suffered from a condition called gynecomastia, a condition in which a man grows male breast tissue due to a hormonal imbalance. Men with gynecomastia have a higher risk of male breast cancer, and the safety labeling now warns of this possible life-threatening side effect. Gynecomastia is caused the body’s production of a female sex hormone, estrogen. It can also contribute to female-pattern weight gain and muscle atrophy.
Finasteride also makes massive changes to the male prostate, a male endocrine gland responsible for semen production. Finasteride can cause prostatic involution, in which the prostate atrophies and prostate cells begin to die. Side effects of this may manifest as decreased semen volume, erectile dysfunction, changes to the physical appearance of the penis, possible nerve damage, and more.
Many men who suffer from Post-Finasteride Syndrome also complain of emotional, mental side effects. Finasteride can make changes to the neurosteroids in the brain that normally ward off depression. By inhibiting these neurosteroids, finasteride may be responsible for symptoms such as anxiety, confusion, and depression.
Symptoms of Post-Finasteride Syndrome
Symptoms of Post-Finasteride Syndrome may include, but are not limited to:
- Endocrine system crash
- Low testosterone
- Low levels of other hormones
- Hormonal imbalance, including increase of estrogen (which can cause body disfigurement or gynecomastia)
- Depression, emotional changes, which may lead to suicide
- Decreased sex drive
- Erectile dysfunction, impotence
- Loss of sensation in the penis
- Loss of spontaneous erections (morning, nocturnal)
- Muscle atrophy, physical weakness
- Shrinkage of the penis and scrotum
- Penile tissue changes
- Problems sleeping
- Memory impairment
- Cognitive impairment
- Emotional trauma
- Other sexual side effects
Do I have a Post-Finasteride Syndrome Lawsuit?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $60 million in verdicts and/or settlements. Please use the form below to contact us for a free Post-Finasteride Syndrome lawsuit review.