Nexium and other heartburn drugs in the PPI class have been associated with higher rates of kidney failure, nephritis (inflammation), and chronic kidney disease. A growing number of lawsuits accuse drug-makers of failing to warn consumers about the risk.
Need a Texas Heartburn Drug Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with kidney damage, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
Heartburn medications prevent a painful condition called “acid reflux” in which stomach acid overflows into the esophagus. Antacids work by neutralizing stomach acid. H2-blockers and Proton Pump Inhibitors (PPIs) decrease the amount of acid made by glands in the stomach.
Proton Pump Inhibitors
- Aciphex (rabeprazole)
- Dexilant (dexlansoprazole)
- Nexium (esomeprazole)
- Prevacid (lansoprazole)
- Prilosec (omeprazole)
- Protonix (pantoprazole)
- Vimovo (naproxen / esomeprazole)
- Zegerid (omeprazole / sodium bicarbonate)
What is the problem?
There is growing evidence that long-term use of PPI heartburn drugs increases the risk of kidney damage. The first case reports were published in the 1990s. Hundreds of cases have occurred since then. In December 2014, the FDA strengthened warnings about acute interstitial nephritis on the labels for all heartburn drugs in the PPI class.
Acute Interstitial Nephritis
Acute interstitial nephritis causes sudden swelling and inflammation in the kidneys, usually due to an allergic reaction to medications in the bloodstream. In severe cases, nephritis permanently decreases kidney function or causes kidney failure. Long-term use of PPIs was associated with a tripled increased risk of nephritis in a study published by CMAJ Open in April 2015.
Chronic Kidney Disease
Chronic Kidney Disease (CKD) is a progressive loss of kidney function over time. Toxins gradually build up in the body and cause health problems. Patients often undergo years of dialysis while awaiting a kidney transplant. People with atherosclerosis who took a PPI twice a day had a 50% higher risk of CKD in a study published by JAMA Internal Medicine in January 2016.
Kidney Failure and ESRD
Kidney failure, also known as End-Stage Renal Disease (ESRD), can occur suddenly or develop gradually. It occurs when the kidneys stop cleaning the blood and performing other basic functions, which can be deadly. Patients on PPIs were 96% more likely to develop kidney failure compared to patients on H2-blockers, according to a study published by the American Society of Nephrology in April 2016.
Symptoms of Kidney Damage
- Nausea, vomiting
- Loss of appetite
- Fatigue and weakness
- Trouble sleeping
- Increased or decreased urination
- Muscle twitches or cramps
- Swelling in feet or ankles
- Chest pain
- High blood pressure
- And more
Need a Heartburn Drug Lawyer in Texas?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas heartburn drug lawyers for a free lawsuit review.