Dexilant is a heartburn drug that has been linked to nephritis (kidney inflammation) and other severe side effects. Recent studies have also suggested it may increase the risk of chronic kidney disease.
Need a Texas Dexilant Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with kidney failure, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
UPDATE: Dexilant Lawsuits Centralized in MDL
August 2017 — Judges have centralized 161 lawsuits involving kidney injuries from Dexilant and other PPI heartburn drugs into Multi-District Litigation (MDL No. 2798) under Judge Claire C. Cecchi in the District of New Jersey — In RE: Proton-Pump Inhibitor Products Liability Litigation (No. II). Drug-makers are accused of failing to warn that Dexilant can cause kidney injuries, Chronic Kidney Disease (CKD), acute interstitial nephritis, end-stage kidney disease, or kidney failure.
Study Links Heartburn Drugs and Death
July 2017 — A new study published in BMJ Open has found up to a 50% increased risk of death for people who use PPI heartburn drugs for 1-2 years instead of another type of heartburn drugs called H2-blockers. long-term use of PPI heartburn drug. Click here to read more.
Heartburn Drugs Causing Massive Health Problems
Dexilant Linked to 96% Higher Risk of Kidney Failure
April 2016 — A study published in the Journal of the American Society of Nephrology has linked the use of anti-heartburn medications in the PPI class to a 96% increased risk of kidney failure and a 26% increased risk of chronic kidney disease. Click here to read more.
Dexilant contains dexlansoprazole, a medication that treats gastroesophageal reflux disease (GERD). It stops heartburn and acid reflux by reducing the amount of stomach acid. Dexilant is manufactured by Takeda Pharmaceuticals and it was approved in January 2009. It was formerly known as Kapidex before a name-change in March 2010.
What is the problem?
Dexilant and other proton-pump inhibitors (PPIs) have been linked to several kidney diseases that can lead to kidney failure without treatment. No one knows why PPIs are associated with kidney problems, but there are several theories. One is that PPIs progressively damage the kidneys by causing low-level inflammation (nephritis). Another theory is that low magnesium levels damage the kidneys.
Dexilant and Nephritis
In December 2014, the FDA updated the label on Dexilant to include new warnings about kidney problems. The FDA warned that patients on Dexilant can develop nephritis (kidney inflammation) at any time during treatment.
The FDA concern was based on a systematic review published in 2007 that identified 64 cases of nephritis associated with PPIs. Eight months later, patients showed improvement but continued to have kidney problems (elevated creatinine levels). Although Dexilant was not on the market at the time of the study, it suggested a class effect.
Acute interstitial nephritis, a hypersensitivity reaction in the kidneys. It is usually caused by an allergy to medications in the blood. It causes sudden inflammation and swelling in the spaces between tubules in the kidneys, and symptoms include:
- Blood in the urine
- Increased or decreased urine output
- Mental status changes (drowsiness, confusion, coma)
- Nausea, vomiting
- Swelling of the body
- Weight gain from fluid retention
Dexilant and Chronic Kidney Disease
Many people take heartburn medications every day. Because they reduce stomach acid, they can interfere with digestion and cause nutritional deficiencies. There is also evidence that daily doses could increase the risk of Chronic Kidney Disease (CKD) by 20-50%.
Dr. Morgan Grams, an assistant professor of epidemiology at Johns Hopkins University in Baltimore, published a study linking heartburn drugs to long-term kidney damage. After analyzing data on more than 10,000 people, researchers found that twice-daily use of PPIs was associated with a 46% increased risk of CKD, versus a 15% increased risk in people taking one daily dose.
Study Finds Risk of Nephritis and Kidney Injury
A study published in the journal of the Canadian Medical Association in April 2015 found that older adults on long-term treatment with PPIs were 2.4-times more likely to develop acute kidney injury, and 3-times more likely to develop nephritis. The study was based on data from 290,000 adults over 66 years old in Canada who started taking PPIs between 2002 and 2011.
Other FDA Safety Warnings for Dexilant
Dexilant and other heartburn drugs in the PPI class have been linked to the following side effects in several FDA Safety Warnings:
- Bone fractures
- Hip, wrist, and spinal fractures
- Vitamin B12 deficiency
- Chronic diarrhea from Clostridium difficile infections
- Low magnesium
- Muscle spasms
- Irregular heartbeat
Dexilant Class Action
The Clark Firm, LLP is nationally recognized as a class action law firm. However, instead of a Dexilant class action, we are filing individual lawsuits. The problem with class actions is that they are not designed to maximize compensation for individual plaintiffs with very serious injuries. We focus our efforts on helping people with severe injuries seek justice and compensation for their pain and suffering, medical expenses, and more.
Need a Dexilant Lawyer in Texas?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Dexilant lawyers for a free lawsuit review.