Zegerid and other anti-heartburn drugs in the proton-pump inhibitor (PPI) class have been linked to nephritis (kidney inflammation), kidney failure, bone fractures, and other severe side effects.
Need a Texas Zegerid Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with kidney failure, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
UPDATE: Zegerid Linked to 96% Higher Risk of Kidney Failure
April 2016 — A study published in the Journal of the American Society of Nephrology has linked the use of anti-heartburn medications in the PPI class to a 96% increased risk of kidney failure and a 26% increased risk of chronic kidney disease. Click here to read more.
What is Zegerid?
Zegerid (omeprazole / sodium bicarbonate) is a medication made by Salix Pharmaceuticals for the treatment of gastroesohageal reflux disease (GERD), also known as heartburn or acid reflux. It works by neutralizing acid and decreasing the amount of acid made by the stomach.
Zegerid and Nephritis
Zegerid is in the Proton Pump Inhibitor (PPI) class of heartburn drugs. In December 2014, the FDA updated warnings on all PPIs to include acute interstitial nephritis, a sudden type of kidney inflammation. Nephritis can occur at any point during treatment and Zegerid should be discontinued if it develops.
Case Reports Link Omeprazole and Nephritis
Zegerid contains omeprazole (Prevacid), a medication that was first linked to nephritis in case reports published in the 1990s. By 2001, omeprazole was associated with 17 case reports of nephritis. On average, nephritis was diagnosed after taking 20-40 mg daily doses every day for 2.7 months. Common symptoms include fatigue, fever, weight-loss, and nausea.
What is Nephritis?
Acute interstitial nephritis is a kidney disease in which the spaces between tubules become swollen and inflamed. It is often caused by an allergic reaction to medications like Zegerid in blood that is being cleaned by the kidneys.
Study Links Zegerid and Chronic Kidney Disease
In February 2016, a study published in JAMA Internal Medicine found a 20-50% increased risk of chronic kidney disease associated with PPIs. Compared to people who used non-PPI heartburn drugs, twice-daily doses of PPIs were associated with a 46% increased risk of kidney disease. The conclusions of the study were based on data from 10,500 people who used heartburn medications.
PPIs Linked to Nephritis and Kidney Injury
In April 2015, the Canadian medical journal CMAJ Open published a study linking the use of PPIs with nephritis and kidney injury. After analyzing data on 290,000 adults over 66 years old in Ontario on long-term treatment with PPIs, they found a tripled increased risk of nephritis and a 2.4-fold increased risk of acute kidney injury.
Symptoms of Kidney Disease
- Nausea, vomiting
- Loss of appetite and weight-loss
- Fatigue and weakness
- More or less urine output
- Muscle aches
- Swelling of feet and ankles due to fluid retention
- Persistent itching
- High blood pressure
Complications of Kidney Disease
The kidneys are responsible for cleaning the blood, removing excess fluids, balancing blood chemistry, and other functions. Kidney problems can cause complications in nearly every part of the body. These include high blood pressure, anemia (low blood count), weak bones, poor nutritional health, and nerve damage. Kidney disease and nephritis can lead to kidney failure. When this occurs, the only treatment is dialysis or a kidney transplant.
Zegerid Side Effects
The FDA has issued numerous warnings about side effects of PPI heartburn drugs like Zegerid. These risks include:
- Acute interstitial nephrtitis
- Bone fractures
- Hip, wrist, and spinal fractures
- Vitamin B12 deficiency
- Chronic diarrhea from Clostridium difficile infections
- Low magnesium
- Muscle spasms
- Irregular heartbeat
Zegerid Class Action
The Clark Firm, LLP is nationally recognized as a class action law firm, but our lawyers are currently filing individual lawsuits rather than a class action lawsuit against the manufacturers of Zegerid. We are evaluating cases involving kidney side effects, such as nephritis and kidney failure.
Need a Zegerid Lawyer in Texas?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Zegerid lawyers for a free lawsuit review.