Texas lawyer for Invokana ketoacidosis, kidney failure, heart attack, and stroke.Pyelonephritis is a life-threatening kidney infection that can occur in patients on diabetes drugs like Invokana. The FDA has received 19 reports of this side effect and warms patients to seek immediate medical attention for symptoms of a urinary infection.

Need a Texas Pyelonephritis Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with a kidney infection after taking Invokana, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.

FDA Safety Warning

In December 2015, the FDA issued a Safety Communication to warn about the risk of pyelonephritis from diabetes drugs in the SGLT2 inhibitor class.

The agency received 19 reports of patients who developed life-threatening blood infections (urosepsis) and kidney infections (pyelonephritis) that started as urinary tract infections. All 19 patients were hospitalized and some required dialysis or intensive care.

SGLT2 Inhibitor Diabetes Drugs

What is the problem?

Diabetes drugs in the SGLT2 inhibitor class were first approved in March 2013. They control blood-sugar levels by forcing the kidneys to remove more sugar from the body in urine.

Unfortunately, excessively frequent and sugary urine significantly increases the risk of urinary tract infections (UTIs) and vaginal yeast infections in women. These infections sometimes spread from the bladder to the kidneys and cause pyelonephritis.

What is Pyelonephritis?

Pyelonephritis is a kidney infection. It can be caused by many types of bacteria or viruses, but most common cause is E. coli that travels into the kidneys from the bladder.

Warning Signs & Symptoms

  • Fever
  • Nausea, vomiting
  • Pain in the back, side, or groin area
  • Chills
  • Frequent and painful urination


Pyelonephritis can cause permanent scarring in the kidneys, which makes it harder for the kidneys to do their job. This can cause complications like high blood pressure, Chronic Kidney Disease (CKD), and kidney failure. In rare cases, bacteria enters the bloodstream and causes sepsis, which is a life-threatening whole-body reaction to toxins in the blood. Patients can go into “septic shock,” in which blood pressure plummets and organs fail.

Diagnosis & Treatment

Treatment begins with a urine culture to identify the type of bacteria that is causing the infection. Doctors will prescribe the most appropriate antibiotic, which is usually taken for 6 weeks. For severe infections, patients may need to be hospitalized to receive intravenous (IV) antibiotics, fluids, and other medications.

Need a Pyelonephritis Lawyer in Texas?

Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.

Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”

The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas pyelonephritis lawyers for a free lawsuit review.