Zofran and Ventricular Septal Defect

Zofran Ventricular Septal DefectSeveral recent studies have found that pregnant women who use Zofran are more likely to have a baby with a ventricular septal defect, which is a life-threatening “hole in the heart” defect.

Need a Texas Zofran Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If your baby was born with a heart defect, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit in Texas.

Zofran and Ventricular Septal Defect

Zofran (ondansetron) is often used during the first trimester to prevent morning sickness caused by pregnancy. The first trimester is also when most major heart defects occur.

Unfortunately, a growing number of studies suggest that Zofran may increase the risk of birth defects. In December 2014, Reproductive Toxicology published a study linking Zofran with a 62% increased risk of heart defects.

The study also linked the use of Zofran in early pregnancy with a doubled risk of cardiac septal defects, including atrial septal defect and ventricular septal defect.

In 2013, another study involving 900,000 pregnancies in Denmark from 1997-2010 found a 30% increased risk of major birth defects associated with Zofran, mostly due to a doubled risk of heart defects.

What is Ventricular Septal Defect?

Ventricular Septal Defect (VSD) is a “hole in the heart” defect that occurs when there are holes in the wall (“septum”) that normally separates the two lower chambers of the heart. The defect occurs during the first eight weeks of pregnancy.

Complications

Normally, the bottom-right chamber of the heart (right ventricle) is responsible for pumping oxygen-poor blood from the body into the lungs. Oxygen-rich blood from the lungs passes through the lower-left chamber (left ventricle) and is pumped into the body through the aorta.

When there is a hole between the left and right ventricles, oxygen-rich blood mixes with oxygen-poor blood. This results in mixed blood being pumped into the body. The heart must work harder to compensate, resulting in higher blood pressure in the lungs (pulmonary hypertension).

Over time, pulmonary hypertension permanently damages delicate blood vessels in the lungs. The muscle in the right ventricle can also thicken, lose flexibility, and weaken until it is no longer able to pump blood effectively. This can lead to deadly heart failure.

Symptoms

  • Heart murmur (abnormal sound heard with a stethoscope)
  • Fatigue
  • Sweating
  • Rapid and heavy breathing
  • Poor feeding or tiring easily while feeding
  • Failure to gain weight or thrive

Need a Zofran Lawyer in Texas?

Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.

Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”

The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Zofran lawyers for a free lawsuit review.

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