Otuska Pharmaceuticals sells Rexulti (brexiprazole), an antipsychotic drug that may increase a patient’s risk of gambling addiction and uncontrollable urges to eat, shop, or have sex.

Rexulti and Abilify

Rexulti (brexpiprazole) is an antipsychotic drug from Otsuka Pharmaceuticals that is highly similar to another antipsychotic drug called Abilify (aripiprazole). In fact, Rexulti was introduced around the same time Otsuka lost patent protection for Abilify.

Rexulti and Gambling Addiction

The label (PDF) on Rexulti does not warn that gambling addiction is a potential side effect, but it does mention that “pathological gambling” has been reported with similar antipsychotic medication. The label on Rexulti recommends telling your doctor about gambling problems.

FDA Warnings for Compulsive Behaviors

Drug-makers updated the label on Abilify to include warnings about “pathological gambling” in Europe in 2012 and in Canada in 2015, but not in the U.S. until May 2016. That was when the FDA ordered drug-makers to warn consumers about impulse-control disorders that can cause uncontrollable urges to gamble, eat, shop, and have sex.


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