Nesina belongs to a class of diabetes medications called incretin mimetics that may increase the risk of pancreatic side effects, including chronic inflammation (pancreatitis) and deadly pancreatic cancer.
Need a Texas Nesina Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with pancreatic cancer, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
Pancreatic Cancer Risks of Nesina
Nesina (alogliptin) belongs to a class of diabetes drugs called incretin mimetics, which mimic digestive hormones called incretins. These hormones stimulate the pancreas to make more insulin, which helps prevent hyperglycemia. Nesina relies on the pancreas to work, which could increase the risk of severe pancreatic side effects, such as:
- Chronic pancreatitis
- Hemorrhagic pancreatitis
- Necrotizing pancreatitis
- Pancreatic cancer
- Pre-cancerous growths (pancreatic duct metaplasia)
FDA Investigates Studies of Pancreatic Risks
In February 2013, sitagliptin and exenatide were linked to a doubled increased risk of pancreatitis in a study published by JAMA Internal Medicine. The following month, the FDA issued a Safety Communication for Nesina. The agency said it was investigating the risk of pancreatitis and studies linking it to a possible risk of pancreatic cancer. However, the agency did not order stronger warning labels.
What is Pancreatic Cancer?
Pancreatic cancer is a rare but often life-threatening disease that occurs when cells start growing uncontrollably and form a mass called a tumor inside an organ called the pancreas.
The pancreas is a digestive gland located below the stomach, deep inside the abdomen. It is responsible for secreting digestive enzymes that break down food and hormones like insulin that tell cells to start using blood-sugar for energy.
Symptoms of Pancreatic Cancer
Pancreatic cancer has no symptoms in its early stages. Even in late stages, symptoms may be non-specific, such as a lack of appetite. Many people only seek medical attention after it blocks a duct or spreads to other organs. Symptoms may include:
- Abdominal pain (pancreas is located below the stomach)
- Back pain
- Indigestion or bloating (especially after fatty foods)
- Gastrointestinal discomfort
- Nausea, vomiting
- Lethargy or weakness
- Unintentional weight-loss
- Loss of appetite
- Blocked bile ducts may cause jaundice (yellow skin and eyes), darkening of the urine, itching, and clay-colored stool
Delayed Diagnosis May Worsen Outlook
Pancreatic cancer is one of the deadliest cancers because it rarely produces symptoms in its early stages. This usually delays diagnosis and treatment until after it has already spread to other organs (metastasized). Because the pancreas is located so close to other vital organs, it is very difficult to treat once it has spread.
Treatment for Pancreatic Cancer
After surgery, there is a risk the cancer will come back. Surgery for pancreatic cancer may be combined with radiation therapy and/or chemotherapy. Radiation therapy uses high-energy x-rays to destroy cancer cells. Chemotherapy uses drugs to destroy cancer cells by stopping their ability to grow and divide.
Need a Nesina Lawyer in Texas?
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