Injectafer is linked to severely low phosphate levels in the blood (a condition called “hypophosphatemia”) and other life-threatening side effects.
Need a Texas Injectafer Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with severe side effects of Injectafer, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
Injectafer® is an iron injection for adults with anemia that was introduced by Daiichi Sankyo in 2013. In recent years, a growing number of lawsuits have been filed by people who developed low phosphate levels after receiving Injectafer.
Injectafer Label Updated With Low Phosphate Warnings
Despite a large amount of evidence linking Injectafer with low phosphate levels, the label did not warn about this risk until February 2020, when the FDA ordered drug-makers to add “Symptomatic Hypophosphatemia” onto the list of potential adverse reactions.
What is the Problem?
Unfortunately, the label still does not explain how severe the low phosphate levels from Injectafer can get — or the substantially increased risk of hypophosphatemia compared to other iron injections.
Injectafer Linked to Increased Risk of Hypophosphatemia
In February 2020, a major clinical trial found that 75% of patients on Injectafer developed low phosphate levels (2.0 mg/dL or less), compared to only 8% of patients on an iron injection called Monoferric.
Furthermore, one of the studies found that 11.3% of patients on Injectafer developed severe hypophosphatemia, versus ZERO patients on Monoferric.
Source: Wolf M, et al., “Effects of Iron Isomaltoside vs Ferric Carboxymaltose on Hypophosphatemia in Iron-Deficiency Anemia: Two Randomized Clinical Trials” JAMA. 2020; 323(5)423-443 (Feb. 2020).
Signs of Low Phosphate Levels
- Extreme fatigue
- Bone softening (osteomalacia)
- Bone fractures
- Cardiac arrest
- Muscle weakness (rhabdomyolysis)
- Muscle pain
- Respiratory failure
- Heart failure
- Irregular heart rhythm (arrhythmias)
- Confusion and delirium
What is Injectafer?
Injectafer® (generic name: ferric carboxymaltose) is an iron injection for adults with anemia. It is given as an intravenous (IV) infusion of two 750-mg doses, at least 7 days apart.
Injectafer is approved for anemic adults who can’t take oral iron pills, or adults who are not on dialysis who are suffering from anemia due to chronic kidney disease.
Injectafer vs. Other Types of Iron Injections
Injectafer is one of several types of iron injections that are available in the U.S., but it is the only one that contains Ferric Carboxymaltose (FCM).
Unlike other iron injections, FMC is associated with severe reductions in phosphate (phosphorus) levels in the body. This can lead to a life-threatening condition called Hypophosphatemia (HPP).
Dangerously Low Phosphate — Hypophosphatemia (HPP)
Hypophosphatemia (HPP) is when the level of phosphate in the blood is too low. In severe or long-term cases, it can cause permanent disability or death.
Mild vs. Severe Hypophosphatemia
Phosphate is one of the body’s electrolytes, which are minerals in the blood. In mild long-term cases of hypophosphatemia, the bones can weaken, resulting in bone pain and fractures. People may also become weak and lose their appetite.
When the amount of phosphate in the blood becomes very low, severe symptoms can occur, such as muscle weakness, followed by confusion, delirium, coma, and death.
Need an Injectafer Lawyer in Texas?
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