The fluoroquinolone antibiotic Avelox may double or triple the risk of aortic aneurysm, according to two recent studies. Aneurysms may have no symptoms until they burst open and cause severe internal bleeding and death.
Need a Texas Avelox Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with an aortic aneurysm, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
Avelox and Aortic Aneurysms
A study published by JAMA Internal Medicine in October 2015 suggests that Avelox may increase the risk of aortic aneurysm. Current users of fluoroquinolone antibiotics were 2.4-times more likely to develop aortic aneurysms within 60 days, and past users had a 50% higher risk.
The study was conducted by researchers in Taiwan who analyzed data on 147,700 people who used antibiotics between January 2000 and December 2011, including 1,477 people who had aortic aneurysms or dissection.
Avelox and other fluoroquinolone antibiotics can damage collagen in connective tissue, which is why they are associated with tendon ruptures and retinal detachment. The study suggests Avelox may also harm connective tissue in the wall of the aorta. According to researchers:
“As fluoroquinolones may induce degradation of collagen causing tendinopathy, this raises the concern that fluoroquinolones may cause or aggravate aortic aneurysm and dissection by a similar mechanism.”
Avelox May Triple Risk of Aortic Aneurysm
In November 2015, the British Medical Journal published a study linking fluoroquinolone antibiotics with a tripled increased risk of aortic aneurysms. Conclusions were based on data from about 650,000 adults over 65 in Canada who used fluoroquinolone antibiotics between April 1997 and March 2012. Of those, 2.1% experienced tendon ruptures, 0.2% experienced retinal detachment, and 1.1% (18,391) experienced aortic aneurysms.
What is an Aneurysm?
An aneurysm is an abnormal bulge or “ballooning” in an artery due to a weak spot in the wall of the blood vessel. As blood flows through the aorta, the weak area bulges like a balloon and can burst if it gets too big.
When the aneurysm ruptures, it causes severe internal bleeding that can rapidly cause death. About 15,000 people in the United States die from aortic aneurysms every year. High blood pressure increases the risk of abdominal aortic aneurysms.
What is an Aortic Aneurysm?
The aorta is a major artery that carries oxygen-rich blood from the heart to the body. It originates in the left ventricle of the heart and extends down to the abdomen. An aortic aneurysm is a blood-filled bulge in the lower part of the aorta near the stomach area.
Warning Signs & Symptoms
Aneurysms are often called the “silent killer” because there are usually no obvious symptoms until it bursts. When symptoms do appear, they may include:
- Abdominal pain (may be constant or come and go)
- Lower back pain that may radiate to groin, buttocks, or legs
- Feeling a “heartbeat” or pulse in the abdomen
Aneurysms that rupture will cause severe pain, low blood pressure, rapid heartbeat, and light-headedness. Symptoms of an abdominal aneurysm may include:
- Severe back or abdominal pain that begins suddenly
- Dry mouth or skin and excessive thirst
- Nausea and vomiting
- Shock – low blood pressure, dizziness, sweating, rapid heartbeat
Need an Avelox Lawyer in Texas?
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The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Avelox lawyers for a free lawsuit review.