Prilosec and other anti-heartburn drugs are available over-the-counter, but they have severe side effects. The FDA has recently warned about acute interstitial nephritis, a type of kidney inflammation that can cause permanent renal impairment.
Need a Texas Prilosec Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with acute interstitial nephritis, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
Acute interstitial nephritis is a kidney disease it causes sudden inflammation and severe swelling in the kidneys. It primarily affects interstitial tissue in the spaces between tubules, which are structures that help the kidneys reabsorb water as they clean the blood.
What Causes Nephritis?
Over 100 medications are known to cause acute interstitial nephritis, including Prilosec. It is generally caused by an allergic reaction to medications in the blood. Patients will need to stop taking all of these medications before they get better.
What is the problem?
Prilosec is an anti-heartburn drug in the Proton-Pump Inhibitor (PPI) class. Evidence linking PPIs and nephritis has been growing since the early 1990s when the first case reports were published.
FDA Updates Prilosec Warnings
After dozens of cases were reported, the FDA updated the label on Prilosec to include acute interstitial nephritis in December 2014.
Just a few months later, a study of nearly 300,000 older adults in Canada found that those on PPIs were three times more likely to develop nephritis than people who did not use PPIs. In another study published by JAMA Internal Medicine in 2016, researchers found a 50% increased risk of nephritis associated with twice-daily use of PPIs.
Symptoms of Nephritis
The symptoms can occur in less than a week, but it usually takes a few weeks before patients are sick enough to go to the hospital. The symptoms may include:
- Enlarged kidneys
- Urinating very frequently or infrequently
- Urine is bloody or cloudy
- Fatigue and tiredness
- Skin rash
- Fluid retention
- Swelling and weight-gain
Complications of Nephritis
Patients who receive prompt treatment can usually recover near-normal kidney function within a few months. However, scarring (fibrosis) is common and many patients have permanent kidney problems. The longer the patient continues taking Prevacid, the higher the risk of kidney failure. After the kidneys have failed, the only treatments are dialysis (using a machine to clean the blood) or a kidney transplant.
Need a Prilosec Lawyer in Texas?
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