December 22, 2016 — The number of lawsuits involving people who experienced severe bleeding after taking Xarelto has topped 15,000 in state and federal court.
As of December 15, there were 14,465 Xarelto lawsuits pending in one federal court in Louisiana — Multi-District Litigation (MDL No. 2592).
More than 1,000 additional lawsuits have been coordinated in a state-level “mass-tort” in the Philadelphia Court of Common Pleas.
Trials are scheduled to start in March 2017 in the federal litigation. The first state-court trial will begin in late 2017, unless lawyers negotiate a settlement or other resolution.
All of the lawsuits accuse drug-makers of downplaying the risk of severe bleeding. The litigation resembles one involving Pradaxa, another blood-thinner linked to serious bleeding.
In 2011, 4,000 lawsuits involving uncontrollable bleeding from Pradaxa settled for $650 million, or an average of $162,500 per case. An antidote to Pradaxa — Praxbind — was approved last year.
An antidote to Xarelto — andexanet alfa — has shown promise in clinical trials, but the FDA denied approval in August over concerns about manufacturing issues. The manufacturer estimates that 100,000 patients who experience severe bleeding on Xarelto will need the medication every year.
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