Nexium is associated with acute interstitial nephritis, which involves sudden inflammation and swelling in the kidneys. It is caused by an allergic reaction and sometimes causes kidney failure.
Need a Texas Nexium Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with acute interstitial nephritis, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit.
What is Nexium?
Nexium contains esomeprazole, an antacid drug in the Proton Pump Inhibitor (PPI) class. It helps treat heartburn and stomach ulcers by decreasing the amount of acid in the stomach.
What is the problem?
Evidence linking PPIs and nephritis has been growing for decades. One of the first case reports was published in 1992. In October 2004, AstraZeneca said it was aware of at least 15 cases of interstitial nephritis possibly caused by Nexium.
Nexium and Acute Interstitial Nephritis
The label on Nexium was updated by the FDA to include acute interstitial nephritis in December 2014. It can occur at ant point during PPI therapy and is generally attributed to a hypersensitivity reaction. Patients who develop nephritis should stop taking Nexium.
What is Acute Interstitial Nephritis?
Acute interstitial nephritis involves sudden inflammation and swelling in the kidneys, usually due to an allergic reaction to medications in the bloodstream. It can lead to chronic kidney problems, or even kidney failure.
Symptoms of Nephritis
The symptoms can appear within a few days, but usually take several weeks after initial exposure to Nexium.
- Enlarged kidneys
- Blood in the urine
- Fever
- Abdominal pain
- Increased or decreased urine output
- Changes in mental status (confusion, coma, etc.)
- Fatigue
- Rash
- Swelling of the body, any area
- Weight gain (from retaining fluid)
Treatment & Prognosis
Patients with nephritis will be hospitalized, where they will receive corticosteroids (anti-inflammatory medications). Kidney function usually recovers within 6-8 weeks when Nexium is discontinued, although some residual scarring (fibrosis) is common. In severe cases, patients never recover normal kidney function. They may require dialysis or even a kidney transplant.
Need a Nexium Lawyer in Texas?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Nexium lawyers for a free lawsuit review.