Januvia (sitagliptin) has been linked to two cases of necrotizing pancreatitis, according to the U.S. Food and Drug Administration (FDA). This severe complication of acute pancreatitis occurs when inflamed pancreatic tissue is permanently damaged or destroyed.
Do I Have a Texas Januvia Lawsuit? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was injured by Januvia necrotizing pancreatitis, you should contact our lawyers immediately. You may be entitled to compensation by filing a Januvia lawsuit in Texas.
Januvia and Necrotizing Pancreatitis
Januvia (sitagliptin) is a medication that is manufactured by Merck & Co. to treat type-2 diabetes. The active ingredient in Januvia, sitagliptin, belongs to a new class of drugs that inhibit dipeptidyl peptidade-4 (DPP-4). This helps a diabetic person control their blood-sugar levels by stimulating the pancreas to produce more insulin (a hormone that lowers blood-sugar).
Unfortunately, it is suspected that Januvia could also increase the risk of sudden inflammation in the pancreas (acute pancreatitis) in some individuals. If the inflammation is not reduced, within a few days, pancreatic tissue can be permanently destroyed. This can lead to necrotizing pancreatitis in Januvia patients.
What is Necrotizing Pancreatitis?
Necrotizing pancreatitis occurs when inflamed pancreatic tissue breaks down, which can cause severe cell damage and tissue death. It is a life-threatening complication that occurs when inflammation from acute pancreatitis is not reduced for many days or weeks. It can also occur in combination with severe bleeding in the pancreas (hemorrhagic pancreatitis).
FDA Warning for Januvia Necrotizing Pancreatitis
The U.S. Food and Drug Administration (FDA) published this Drug Safety Communication to warn about the possible link between Januvia and necrotizing pancreatitis:
“Eighty-eight post-marketing cases of acute pancreatitis, including two cases of hemorrhagic or necrotizing pancreatitis in patients using sitagliptin, were reported to the Agency between October 16, 2006 and February 9, 2009.”
Symptoms of Januvia Necrotizing Pancreatitis
Individuals who take Januvia should be vigilant for symptoms of pancreatitis, which may include:
- Severe, persistent upper-abdominal pain
- Weight loss
- Abdominal swelling and tenderness
- Decreased blood pressure
- And more
In addition to these symptoms, individuals with Januvia necrotizing pancreatitis may exhibit the following symptoms:
- Very low blood pressure (hypotension)
- Increased heart rate, palpitations
- Symptoms of septic shock
- Cold limbs, hands or feet
- Very high or low body temperature
- Shortness of breath
Januvia Necrotizing Pancreatitis Complications
Individuals who develop Januvia necrotizing pancreatitis are at risk of suffering the following complications:
- Infection: Necrotic tissue in the pancreas is highly susceptible to bacterial infection.
- Sepsis: This is a bacterial infection in tissues that can spread to the blood and organs. Severe sepsis involves body-wide inflammation, multiple organ system failure, septic shock, dangerously low blood pressure, and death.
- Pancreatic abscess or pseudocyst is a complication that occurs when necrotic pancreatic tissue dies, liquefies, and becomes infected with bacteria. The abscess is typically a fluid-filled collection that contains large amounts of pus and pancreatic enzymes within a fibrous wall. If an abscess or cyst ruptures, it may spill caustic digestive enzymes into the abdomen and cause severe organ damage.
- Organ failure: Heart, lung, kidney, and other organ failure is responsible for 2/3 of deaths from necrotizing pancreatitis.
- Surgery: If necrotic pancreatic tissue is infected, it is almost always necessary to remove it with surgery. The patient may also be given a shunt to drain infected fluids from the abdomen.
- And more
Do I have a Januvia Lawsuit in Texas?
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Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $60 million in verdicts and/or settlements. Please use the form below to contact us for a free Texas Januvia lawsuit review.