DMBA, Stimulant Similar to DMAA, Found in 12 SupplementsOctober 8, 2014 — LiveScience reports that an untested stimulant similar to DMAA has been found in 12 supplements marketed for weight-loss and bodybuilding.

The study was published in Drug Testing and Analysis by Dr. Pieter A. Cohen, assistant professor of medicine at Harvard Medical School.

He discovered a synthetic stimulant known as 1,3-dimethylbutylamine (DMBA) — a chemical analogue of DMAA, which was recently banned by the U.S. Food and Drug Administration (FDA).

Researchers warn that DMBA might have similar side effects as DMAA, which is known to elevate blood pressure and lead to cardiovascular problems ranging from shortness of breath and tightness in the chest to heart attack.

In April, the FDA issued a warning letter to the manufacturer of Craze after Dr. Cohen found evidence of a methamphetamine-like compound. The manufacturer re-formulated Craze, re-branded it as Frenzy, which is only sold in Europe. Unfortunately, Frenzy has been found to contain DMBA.

Supplements containing DMBA include:

  • Frenzy (Driven Sports, Inc.)
  • Contraband (Iron Forged Nutrition)
  • Redline White Heat and MD2 Meltdown (Vital Pharmaceuticals Inc. or VPX)
  • Evol and Decimate Amplified (Genomyx LLC)
  • Oxyfit Xtreme and Synetherm (
  • AMPitropin and AMPilean (Lecheek Nutrition)
  • OxyphenXR AMP’D (Beta Labs Ltd.)

Other names for DMBA may include:

  • 4-amino-2-methylpentane citrate
  • AMP citrate
  • 1,3-dimethylbutylamine citrate
  • 4-amino-2-pentanamine, Pentergy
  • 4-AMP

Two supplements (Frenzy and OxyPhen XR AMP’D) implied that DMBA was an extract of the Pouchong tea leaves, but the researchers said it would be physically impossible to get enough tea to make even the lowest dose. Synthetic DMBA is easy to synthesize and widely mass-produced for pharmaceutical effects.

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