Tribenzor Sprue-Like Enteropathy InformationOne of the most serious complications of Tribenzor is sprue-like enteropathy, an intestinal disease that causes frequent, watery diarrhea and rapid weight-loss. Although symptoms usually resolve when Tribenzor is discontinued, untreated enteropathy can cause permanent intestinal damage and complications that destroy a person’s health.

Need a Texas Tribenzor Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was injured by sprue-like enteropathy, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit in Texas.

Tribenzor and Sprue-Like Enteropathy

Tribenzor is an anti-hypertensive medication that is prescribed to treat people with high blood pressure. It contains a combination of three drugs, one of which is olmesartan.

In August 2012, Mayo Clinic Proceedings published a study linking olmesartan with 22 cases of chronic diarrhea and severe weight-loss. All of the patients tested negative for Celiac disease (also known as “celiac sprue”) and did not improve on a gluten-free diet. Their condition improved only when they were switched off olmesartan.

Evidence linking Tribenzor and sprue-like enteropathy has continued to grow in recent years. In July 2013, the U.S. Food and Drug Administration (FDA) finally updated the label with the following warning:

“Severe, chronic diarrhea with substantial weight loss has been reported in patients taking olmesartan months to years after drug initiation. Intestinal biopsies of patients often demonstrated villous atrophy. If a patient develops these symptoms during treatment with olmesartan, exclude other etiologies. Consider discontinuation of Tribenzor in cases where no other etiology is identified.”

What Causes Sprue-Like Enteropathy?

No one knows exactly what causes sprue-like enteropathy. However, olmesartan is the only drug in the angiotensin II receptor blocker (ARB) class that is associated with enteropathy. Because onset of symptoms is typically delayed several months or years, it could be a delayed immune response or localized hypersensitivity reaction.


Lawsuits have been filed by people who suffered from sprue-like enteropathy for years. Over time, sprue-like enteropathy can damage the lining of the intestines (a complication known as villous atrophy) and permanently decrease the body’s ability to digest food.


  • Chronic diarrhea (frequent, watery bowel movements)
  • Weight-loss
  • Nausea, vomiting
  • Bloating
  • Dehydration
  • Malnutrition
  • Intestinal villous atrophy
  • Kidney problems
  • Abdominal pain
  • Weakness, fatigue
  • Vitamin and mineral (electrolyte) imbalances
  • And more

Need a Tribenzor Lawyer in Texas?

Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.

Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”

The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Tribenzor lawyers for a free lawsuit review.