The blood-thinning drug Xarelto is associated with a risk of severe, life-threatening internal bleeding. Because it lacks an effective reversal agent, doctors may struggle to stop bleeding after an injury.
Need a Texas Xarelto Lawyer? Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged. If you or a loved one was diagnosed with severe bleeding, you should contact our lawyers immediately. You may be entitled to compensation by filing a lawsuit in Texas.
Xarelto Lawsuit Filed for Uncontrollable Brain Bleeding
June 26, 2014 — A lawsuit (PDF) has been filed on behalf of a man who took Xarelto for atrial fibrillation and died six month later from uncontrollable bleeding in the brain (subdural hemorrhage). Click here to read more.
Bleeding occurs when damage to a vein or artery allows blood to escape the circulatory system. Normally, blood clots clog broken vessels after an injury and allow healing. When heavy bleeding occurs, vital organs do not receive enough blood and start to shut down. This can cause coma (unconsciousness) and death.
Xarelto and Bleeding
Patients who take anti-clotting drugs, such as Xarelto, are more likely to start bleeding when there is no injury. When they do, bleeding is more difficult to stop. The problem is that Xarelto changes blood chemistry. It inhibits Factor Xa, which is a clotting factor that blood platelets require to stick together.
Risks Linked to Xarelto
What is the Risk?
According to the ROCKET AF clinical trial comparing Xarelto to warfarin in over 7,000 patients:
- Major bleeding: Xarelto (5.6%) – Warfarin (5.4%)
- Bleeding in a critical organ: Xarelto (1.3%) – Warfarin (1.9%)
- Fatal bleeding: Xarelto (0.4%) – Warfarin (0.8%)
- Bleeding resulting in transfusion: Xarelto (2.6%) – Warfarin (2.1%)
- Gastrointestinal (GI) bleeding: Xarelto (3.1%) – Warfarin (2%)
Xarelto Bleeding Antidote
When Xarelto was approved in 2011, it was the second new blood-thinner since the FDA approved warfarin in the 1950s. Although warfarin is a problematic drug, one advantage is that doctors can deactivate it with a simple dose of Vitamin K. Xarelto has no such antidote. Not even dialysis (mechanically cleaning the blood) can reverse its anti-clotting effects.
What is Internal Bleeding?
Internal bleeding may occur in tissues, organs, or cavities in the body. Unlike bleeding outside the body, diagnosis of internal bleeding can be much more difficult. Symptoms may only appear after a significant amount of blood has been lost or when organs stop functioning properly.
Symptoms of internal bleeding depend on the location and the amount of blood that has been lost. If too much blood is lost, patients may go into hypovolemic shock, which causes rapid heartbeat, low blood pressure, cold and clammy skin, and mental confusion.
Symptoms of Internal Bleeding
- Bleeding in the brain (cerebral hemorrhage): Headache, vomiting, tiredness, loss of consciousness, seizure, slurred speech, weakness on one side of the body, confusion, changes in vision, tingling or numbness, etc.
- Intestinal bleeding: Dark stools, blood in stools, vomiting blood (may look bright red or like coffee grounds), low blood count.
- Abdominal bleeding: Stomach pain, swelling, chest pain, vomiting blood
- Joint bleeding (haemarthrosis): Severe pain, loss of range of motion, cartilage damage, disability
- And more
Need a Xarelto Lawyer in Texas?
Collen A. Clark is a true advocate for his clients and is passionate about helping Texans that have been injured or wronged.
Collen’s amazing success in the courtroom and well known dedication to his clients has earned him the recognition of his peers as one of The Top Trial Lawyers in Texas.”
The Clark Firm has assembled a team of trial lawyers with more than 100 years experience, participation in over 600 jury trials and $260 million in verdicts and/or settlements. Please use the form below to contact our Texas Xarelto lawyers for a free lawsuit review.