The most serious side effects of Avelox include heart problems, aortic aneurysms, nerve damage, tendon injuries, skin reactions, and death.

What is Avelox?

Avelox (moxifloxacin) is a prescription medication that is used to treat bacterial infections. It is a fluoroquinolone, which is a class of broad-spectrum antibiotics.

Avelox and Heart Problems

Avelox damages collagen and connective tissues all over the body, including the heart. In a recent study, researchers found an increased risk of heart valve damage in patients on fluoroquinolone antibiotics, such as Avelox. Over time, heart valve damage significantly increases the risk of deadly heart problems such as heart failure, heart attacks, and more.

Avelox and Nerve Damage

Avelox is linked to peripheral neuropathy, which is a type of nerve damage that causes numbness, pain, weakness, and other symptoms in the arms and legs. The symptoms can occur within a few days of taking Avelox and last for years.

FDA added warnings about peripheral neuropathy to the label on Avelox in 2004, but these warnings were not strong enough. In 2013, the FDA updated the warnings to emphasize the rapid onset of symptoms and the risk of permanent complications.

Avelox and Aortic Aneurysms

In 2018, the FDA updated the label on Avelox to include warnings about aortic aneurysms (also called “aortic dissections”). This severe side effect occurs when Avelox damages the wall of the aorta, causing it to bulge outward. In some cases, the aorta suddenly rips open, causing massive internal bleeding and often death.

Avelox and Stevens-Johnson Syndrome (SJS)

Patients have died from Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) after taking just a few doses of Avelox, according to the Prescribing Information. These side effects cause a painful skin rash with blisters. Large sections of skin peel off the body. Complications include infections, blindness, organ damage, and death.


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