Striant Deep Vein Thrombosis (DVT) InformationTestosterone replacement products are associated with an increased risk of blood clots in the legs. If you were not aware of the risk of deep vein thrombosis (DVT) from Striant, you are not alone.

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Striant and DVT

Striant is a buccal system for delivering testosterone through the mouth. Unfortunately, testosterone can sometimes cause high red blood cell counts. This can increase the risk of blood clots in the legs and deep vein thrombosis (DVT) by thickening the blood and elevating blood pressure. Before starting Striant, many doctors recommend having a blood test to check for genetic mutations that increase your risk of blood clots. If you develop blood clots, you may need to stop taking Striant.

Deep Vein Thrombosis (DVT) Information

Deep Vein Thrombosis (also called DVT) is a blood clot in a deep vein inside a muscle. These blood clots usually grow in the leg veins in the calf or thigh. While DVT is a fairly common condition, it is also potentially dangerous. If the blood clot breaks away and travels through the bloodstream, it can block blood vessels in the lungs. This is called a pulmonary embolism, and it can be fatal.


About 50% of cases of DVT do not produce symptoms. However, many people with DVT have the following symptoms:

  • Some swelling in one or both legs
  • Pain or tenderness in one leg (may only happen when you walk)
  • Skin feels warm
  • Skin looks red or discolored


  • Ultrasound: This test uses sound waves to create an image of veins in the legs.
  • D-dimer: Blood test checks for substances in the bloodstream that normally dissolve blood clots.
  • Contrast venography: When ultrasound and D-dimer are inconclusive, doctors inject a contrast dye and take an X-ray to better visualize circulation in the legs.
  • Magnetic resonance imaging (MRI): If a pulmonary embolism is suspected, an MRI may be used to create a picture of the body.

Resources & Additional Information

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