Delatestryl Deep Vein Thrombosis (DVT) InformationDeep Vein Thrombosis (DVT) is a serious complication of testosterone replacement products that occurs when blood clots grow deep inside the body. If you were unaware of this risk before starting Delatestryl, you are not alone.

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Delatestryl and Deep Vein Thrombosis (DVT)

Delatestryl is an intramuscular injection of testosterone. For some patients, testosterone increases the number of blood platelet cells, causing blood to clot more easily. An increase in blood platelets may also thicken the blood and elevate blood pressure.

Many testosterone treatments are known to cause blood clots in the legs — also known as deep vein thrombosis or DVT. Therefore, some doctors recommend having a simple blood test to determine if you are at high risk for blood clots before starting testosterone replacement therapy.

What is Deep Vein Thrombosis (DVT)?

Deep Vein Thrombosis (DVT) is a blood clot that forms in a vein deep inside the body. DVT mainly affects blood clots in large veins in the lower leg or thigh, but blood clots can also grow in other areas of the body. The deep veins are surrounded by muscles that force blood into the heart and lungs, with one-way valves that keep blood flowing in one direction.


Only about half of cases of DVT cause symptoms. When symptoms appear, they may be mild or vague, and may include:

  • Red discoloration of the legs
  • Calf or leg pain or tenderness
  • Swelling of the legs
  • Warm skin
  • Surface veins are more visible
  • Leg weakness


  • Post-thrombotic syndrome: Complication of DVT that occurs when the blood clot damages valves in the leg. This irreversible damage causes chronic problems with swelling in the legs, pain, fatigue, skin ulcers, and hardening of the skin.
  • Pulmonary embolism: DVT complication occurs when blood clots travel from the lower legs, through the heart, and into the lungs. May cause shortness of breath, coughing up blood, low oxygen, chest pain, and other symptoms.

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