Clomid Birth Defects

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The fertility drug Clomid has been linked to a 3X increased risk of birth defects and the CDC has warned about higher rates of heart defects, skull defects, and more.

Clomid Birth Defects

Clomid (clomiphene citrate) is a fertility drug that helps women get pregnant by stimulating the ovaries to release an egg. Unfortunately, studies have shown that it also significantly increases the risk of having a baby with a birth defect when used just before or during pregnancy, including:

  • Neural tube (spina bifida)
  • Heart defects
  • Skull defects
  • Gastrointestinal defects (omphalocele)
  • Hypospadia
  • Cleft lip/palate
  • Limb defects
  • And more

Pregnancy Category X

Clomid is “Pregnancy Category X” — the most serious classification the FDA can give a drug to warn about the risk of birth defects. Studies have shown that up to 20% of pregnancies exposed to Clomid end spontaneous miscarriage. Up to 10% involve multiples (twins or triplets).

Study Links Clomid and 3X Risk of Birth Defects

In May 2012, a study published in the New England Journal of Medicine found a tripled risk of birth defects in babies born to women who used Clomid. Birth defects linked to fertility treatments included cardiovascular, musculoskeletal, urogenital, and gastrointestinal defects and cerebral palsy.

CDC Issues Warning for Clomid Birth Defects

In November 2010, the journal Human Reproduction published a study linking Clomid with an increased risk of birth defects.

Conclusions of the study were based on data from the National Birth Defects Prevention Study. It included women who had a baby between October 2007 and December 2005 and used Clomid from 2 months before pregnancy through the first month of pregnancy

Overall, researchers found higher rates of the following birth defects:

 

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