The testosterone underarm product Axiron is known to increase the risk of blood clots in the legs. This condition, also known as deep vein thrombosis (DVT), can lead to a life-threatening pulmonary embolism.
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Axiron and Deep Vein Thrombosis (DVT)
Axiron (testosterone) can cause serious side effects, including blood clots in the legs, according to the safety information provided by the manufacturer, Lilly USA, LLC. This condition, also known as deep vein thrombosis or DVT, can cause pain, swelling, or redness in your legs.
Testosterone and Blood Clots in Legs
Axiron contains 30-mg of testosterone per 1.5-mL. The testosterone in Axiron is absorbed through the skin, it enters the bloodstream and influences hormone levels. One common side effect of testosterone is an increase in the number of red blood cells, which can potentially thicken the blood and elevate blood pressure. These effects increase your risk of developing blood clots in the legs or DVT.
What is Deep Vein Thrombosis (DVT)?
Deep Vein Thrombosis (DVT) is a serious medical condition that occurs when blood clots grow in veins deep inside the body. Almost all cases of DVT occur in the lower legs or thigh, but blood clots can also grow in the pelvis, kidney, arms, or other areas of the body.
- Pain and tenderness over the vein
- Pain or swelling in the part of the body affected
- Skin redness
- Warm skin near the clot
The most serious complication of DVT is a pulmonary embolism. This complication occurs when a blood clot breaks off, travels in the bloodstream, gets pumped through the heart, and ends up blocking a pulmonary artery in the lungs. Symptoms of a pulmonary embolism include sudden chest pain that gets worse when breathing deeply, unexplained shortness of breath, coughing up blood, fast heart rate, and more.
Resources & Additional Information
- What is Deep Vein Thrombosis? — National Heart, Lung, and Blood Institute
- Deep Vein Thrombosis — MedlinePlus
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